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SAMe Supplement Effective at Treating Depression

by: Ethan A. Huff
Researchers recently completed a study revealing that the increasingly popular supplement S-Adenosyl Methionine (SAMe) is an effective treatment for people with depression. The substance, which occurs naturally in the body, exerts influence on the brain in ways that improve brain function, alleviate stress and feelings of depression and reduce inflammation.

DepressionFor the study, scientists administered either 1,600 milligrams (mg) of SAMe or a placebo on top of participants’ existing medication regimens for six weeks. Following this period, the team found that those participants taking SAMe experienced better relief from depression that did those simply taking conventional antidepressants.

And since SAMe is naturally produced in the body, there are no negative side effects from taking it like there are from taking chemical antidepressant drugs.

According to Dr. George Papakostas, author of the study and psychiatrist at Harvard Medical School and Massachusetts General Hospital in Boston, the results are “exciting because [SAMe] works differently than what we have now — it doesn’t seem to be associated with the kind of side effects that FDA-approved treatments for this niche have.”

And this is good news for many who have experienced devastating side effects from taking antidepressants. SAMe is not only a viable alternative to these pharmaceutical drugs, but it exerts many other positive changes within the body as well.

“SAMe is a naturally occurring molecule present in all living cells, and is made in the body by a reaction between methionine and another compound called adenosyntriphosphate (ATP). It has many incredible benefits, including a positive effect on depression and arthritis pain…it helps the liver to replenish important substances, notably the all-important glutathione,” explains Johny Bowden, Ph.D., C.N.S.

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  • Jenica Sy

    SAM e is very effective for me, when my mood is complicated. Sam e can get rid my my depression.

    Sam-e

  • http://www.helpfordepression.com/slideshow/drugs-and-medications/what-are-mao-inhibitors mao inhibitors

    SAM-e, in combination with standard depression treatment, was more effective than antidepressant treatment alone in improving measures of depression and remission rates of patients with significant clinical depression. SAM-e-treated subjects had a greater response and remission rate to treatment than the placebo-treated group. SAM-e was well-tolerated with no reported adverse reactions.

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